Program: DGP
karen.gomez@northwestern.edu
Research Description
Karen is working to develop novel arrestin-biased allosteric modulators for the neurotensin receptor 1 (NTS1), a promising target for treating substance use disorders. Using pharmacophore modeling, virtual screening, and NMR fragment-based drug discovery, she aims to create a framework for engineering pharmacologically distinct GPCR ligands to explore broader mechanisms of allosteric modulation.